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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Product Name
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS No.
1987887-92-2
Chemical Name
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-011;Intedanib Impurity D;Nintedanib Impurity q;Nintedanib Impurity 34;Nintedanib impuritiesD;Nintedanib impurities25;NintedanibN-Methylimpurity;Nintedanib N-Methyl Aniline Analog;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen...
CBNumber
CB13335038
Molecular Formula
C24H21N3O3
Formula Weight
399.44
MOL File
1987887-92-2.mol
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Property

Melting point:
273 - 276°C
Boiling point:
641.3±55.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
11.16±0.20(Predicted)
form 
Solid
color 
Yellow to Orange
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D492443
Product name
(3Z)​-2,​3-Dihydro-​3-​[[[4-​(methylamino)​phenyl]​amino]​phenylmethylene]​-​2-​oxo-​1H-​Indole-​6-​carboxylicAcidMethylEster
Packaging
5mg
Price
$255
Updated
2021/12/16
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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production

Uses

(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Suppliers

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1987887-92-2, (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateRelated Search:

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Nintedanib Methyl oxindole-5-carboxylate N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER Methyl 1-acetyl-2-oxoindoline-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene METHYL OXINDOLE-7-CARBOXYLATE P-ANISALDEHYDE DIMETHYL ACETAL 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate BIBF 1202 N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide Methyl 4-chloro-3-nitrobenzoate

  • Intedanib Impurity D
  • Nintedanib Impurity 34
  • Nintedanib-011
  • Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...
  • 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-
  • Nintedanib Impurity q
  • (3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester
  • (Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (Nintedanib Impurity)
  • (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen...
  • Nintedanib impurities25
  • Nintedanib impuritiesD
  • NintedanibN-Methylimpurity
  • Nintedanib N-Methyl Aniline Analog
  • (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • 1987887-92-2